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Acute Myeloid Leukemia
// The Impact of Myeloid Cells in Disease

Conductors of the Immune System

Myeloid cells are the front lines of defense against disease, responsible for choreographing downstream immune responses. They’re also versatile, with effector functions capable of killing cancer cells. When applied to a therapeutic candidate, immunotherapy is designed to recognize and engulf cancer cells, produce anti-tumor agents, promote anti-tumor adaptive immunity, alter the tumor microenvironment, and ultimately kill cancer.

// Myeloid Platforms

Multidisciplinary Technologies

Our therapies incorporate advanced cell and gene therapy methods, combining immunology, genetics, cell biology, and protein science to improve the lives of patients in need.

01

Our novel in vivo engineering platform targets and activates myeloid cells within solid tumors to elicit broader anti-tumor adaptive immunity — without the need for ex-vivo cell engineering.

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01

In Vivo mRNA Programming

In Vivo mRNA Programming
02

Our retrotransposon-mediated gene-insertion technology offers the potential to deliver larger genetic sequences into the genome than is currently possible with existing technologies.

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02

CREATE Gene-Editing

CREATE Gene-Editing
03

Our mRNA technologies utilize myeloid cells to engulf cancer cells, produce anti-tumor agents, promote anti-tumor adaptive immunity, and alter the tumor microenvironment.

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03

mRNA Cell Therapy

mRNA Cell Therapy
// Our Capabilities

Next-Generation Immunotherapies

Our capabilities translate into unmatched product designs with transformative “full-immune” engagement.

Myeloid Lab